VASO-OCCLUSIVE CRISIS: TREATMENT WITH PHENTOLAMINE. 902

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Breathing patterns during vaso-occlusive crisis of sickle cell disease.

STUDY OBJECTIVES To determine the effect of sickle cell pain and its treatment on patients' breathing patterns, and to compare the effect of thoracic cage pain to pain at other sites. DESIGN Prospective, observational study. SETTING Sickle Cell Center Day Hospital. PATIENTS Twenty-five patients with sickle cell disease admitted to the Sickle Cell Center Day Hospital for treatment of vaso-...

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The vaso-occlusive crisis of sickle cell disease.

Sickle cell anaemia was the first molecular disease to be described'; despite intensive study we still do not understand the relations between the clinical picture, the cellular defects, and the molecular make up of any one person. Two recent papers have further elucidated the complex pathophysiology associated with painful crisis, although their implications for treatment are unclear. Clinicia...

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Sickle cell disease in children: differentiating osteomyelitis from vaso-occlusive crisis.

OBJECTIVE To identify clinical and laboratory features predictive of osteomyelitis in children with sickle cell disease and bony pain. DESIGN Patients in the case group and participants in the control group were randomized in a 1:3 ratio. SETTING The Hospital for Sick Children, Toronto, Ontario, Canada. PARTICIPANTS Patients with sickle cell disease and osteomyelitis (case patients) and p...

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Pancreatitis in the Setting of Vaso-occlusive Sickle Cell Crisis: A Rare Encounter

Acute pancreatitis is a common cause of acute abdominal pain. Gallstones and alcohol abuse account for the majority of the cases. Pancreatic ischemia is an uncommon but established cause of pancreatitis associated with connective tissue diseases, vasculitis, and shock. Our case highlights a rare case of vaso-occlusive crisis (VOC) in a patient with sickle cell (SC) disease leading to pancreatit...

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Monitoring the acute phase response to vaso-occlusive crisis in sickle cell disease.

AIMS To identify suitable acute phase proteins as objective markers of tissue ischaemia during painful vaso-occlusive crises in sickle cell disease. METHODS The prodromal and established phases of 14 vaso-occlusive crises were studied longitudinally in 10 patients with sickle cell anaemia. Automated solid phase enzyme immunoassays were used to measure the fast responding acute phase proteins ...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1996

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-199604001-00924